publications - HUB Organoids

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response

June 20, 2024

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response

J Exp Clin Cancer Res | 2024 Feb

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

October 11, 2023

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

Cell Rep | April 2023

July 20, 2023

Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules

Eur J Pharm Sci | July 2023

Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

February 17, 2022

Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

eLife | July 2021

Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids

February 17, 2022

Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids

J Cyst Fibros | May 2021

Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal

February 17, 2022

Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal

J Vis Exp | July 2021

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

February 16, 2022

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Cell | May 2015

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

February 16, 2022

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Nature | May 2009

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium

February 16, 2022

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium

Gastroenterology | Nov 2011

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

February 16, 2022

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

eLife | Nov 2016