Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

October 11, 2023

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

Cell Rep | April 2023

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Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules

July 20, 2023

Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules

Eur J Pharm Sci | July 2023

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Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

February 17, 2022

Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

eLife | July 2021

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Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids

February 17, 2022

Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids

J Cyst Fibros | May 2021

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Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal

February 17, 2022

Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal

J Vis Exp | July 2021

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Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

February 16, 2022

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Cell | May 2015

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

February 16, 2022

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Nature | May 2009

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Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium

February 16, 2022

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium

Gastroenterology | Nov 2011

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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

February 16, 2022

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

eLife | Nov 2016

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A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

February 16, 2022

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Cell | Jan 2018

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