Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response

June 20, 2024

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response

J Exp Clin Cancer Res | 2024 Feb

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Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

October 11, 2023

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

Cell Rep | April 2023

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Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

February 16, 2022

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Cell | May 2015

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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

February 16, 2022

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

eLife | Nov 2016

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A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

February 16, 2022

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Cell | Jan 2018

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Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

February 16, 2022

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

Nat Protoc | April 2021

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Sequential cancer mutations in cultured human intestinal stem cells

February 16, 2022

Sequential cancer mutations in cultured human intestinal stem cells

Nature | May 2015

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Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

February 16, 2022

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

Nat Cancer | April 2022

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Long-term expanding human airway organoids for disease modeling

February 16, 2022

Long-term expanding human airway organoids for disease modeling

EMBO J | February 2019

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Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

February 16, 2022

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

NPJ Precis Oncol | April 2021

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